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5 edition of Carcinogenic and Chronic Toxic Hazards of Aromatic Amines found in the catalog.

Carcinogenic and Chronic Toxic Hazards of Aromatic Amines

by T. S. Scott

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  • 11 Currently reading

Published by Elsevier Pub. Co. in Amsterdam, New York .
Written in English


Edition Notes

SeriesElsevier monographs on toxic agents, v.26, Edited by E. Browning
The Physical Object
Pagination208 s.
Number of Pages208
ID Numbers
Open LibraryOL24779371M
OCLC/WorldCa475697265

  Aromatic amines are a class of organic compounds that include many members that are carcinogenic, both experimentally in the research setting and experientially in human life. The carcinogenesis literature documents innumerable studies demonstrating that administration of a considerable variety of aromatic amines to experimental animals of Cited by: Aromatic amines are widely used as precursor to pesticides, pharmaceuticals, and dyes. Aromatic amines in textiles. Since August , the new standard EN Textiles - Methods for determination of certain aromatic amines derived from azo colorants - Part 1: Detection of the use of certain azo colorants accessible with and without extracting the fibres is effective.

Current Toxicology Series Series Editors Diana Anderson Tno Bibra International Ltd, Surrey, UK Michael D Waters Consultant, Chapel Hill, NC, USA Timothy C Marrs Department of Health, London, UK Food Borne Carcinogens Heterocyclic Amines Edited by Minako Nagao, Tokyo University of Agriculture, Japan Takashi Sugimura, National Cancer Center, Japan Food Cited by: Primary aromatic amines from printed food contact materials such as napkins or bakery bags BfR Opinion No / of 24 July Some substances in the group of primary aromatic amines (PAAs) are carcinogenic. PAAs can, for example, occur as contaminants in colour pigments. They can pose a health risk in.

Quantitative Structure−Activity Relationships of Mutagenic and Carcinogenic Aromatic Amines Article in Chemical Reviews (10) November with . A new method of separation of carcinogenic aromatic amines in wastewater is given. With SDS (C12H25O4SNa) and β-CD (β-cyclodextrin) addition, it is effective to improve separation. At the same time, it forms mixed micelle. As a result, a micellar electrokinetic capillary chromatography (MECC) system was established. Nine aromatic amines were.


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Carcinogenic and Chronic Toxic Hazards of Aromatic Amines by T. S. Scott Download PDF EPUB FB2

Carcinogenic and chronic toxic hazards of aromatic amines. Amsterdam, New York, Elsevier Pub. [sole distributors for the U.S.: American Elsevier Pub.

Co., New York] (OCoLC) Document Type: Book: All Authors / Contributors: Thomas Smith Scott. Carcinogenic and Chronic Toxic Hazards of Aromatic Amines [T.S.

Scott] on *FREE* shipping on qualifying by:   For personal accounts OR managers of institutional accounts. Username *. Password *Author: R. Schoental.

Book: Carcinogenic and Chronic Toxic)EIazards of Aromatic Amines. + pp. Abstract: The title is a reminder that occupational tumour of the bladder bladder Subject Category: Anatomical and Morphological StructuresCited by: Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Aromatic Amines and 4-Nitrobiphenyl (I a R C Scientific Publication) by n/a and a great selection of related books, art and collectibles available now at Acute and chronic toxicity of aromatic amines studied in the isolated perfused rat liver.

Ambs S(1), Neumann HG. Author information: (1)Department of Toxicology, University of Würzburg, Germany. Isolated perfused livers from male Wistar rats were used to study acute and chronic toxic effects of carcinogenic aromatic by: Dobriner K, Hogmann K, Rhoads CP.

THE METABOLISM OF beta-NAPHTHYLAMINE BY RATS, RABBITS AND MONKEYS. Science. Jun 20; 93 ()– [MANSON LA, YOUNG L.

Biochemical studies of toxic agents; the metabolism of 2-naphthylamine and 2-acetamidonaphthalene. of the aromatic amines In our first QSAR analysis of the carcinogenic-ity of the aromatic amines, we considered only the carcinogenic aromatic amines, and we investigated the structural factors that influence the gradation of carcinogenic potency in rodents [9].

The study fo-cused on the homogeneous class of non-heterocyclic Size: KB. Aromatic amines are aromatic hydrocarbons with amino substituents that usually appear during the thermal treatment of foods with high protein content.

These aromatic amines are also used in dyes, as antioxidants, and as precursors of pharmaceutical products. Figure summarizes the main biotransformation routes of 2-aminonaphthalene.

This chemical can be initially. These observations have since been followed by the identification of the carcinogenic potential of other aromatic amines in humans and animal models, such.

Abstract. Many polycyclic aromatic amines are mutagenic, and their genotoxic properties are held responsible for their biological effects. The genotoxic effects are explained by the formation of metabolites that react with macromolecules by forming adducts (Kriek ; Franz et al.

).Cited by: 5. Aromatic amines are found in industries such as iron, steel, dyes, pharmaceuticals, oil refining, personal household services, textile manufacturing, leather manufacturing, and rubber. [4], [5] They are also found in tobacco smoke, well-cooked meat, hair dye and diesel exhaust and can be produced by burning wood chips.

Aromatic amines also cause bladder cancer whenever they are tested in dogs. The Working Group identified several additional aromatic amines that are carcinogenic to human beings. ortho-Toluidine is used in the production of dyes, pigments, and rubber chemicals, and as a.

Heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs) are chemicals formed when muscle meat, including beef, pork, fish, or poultry, is cooked using high-temperature methods, such as pan frying or grilling directly over an open flame (1).

In laboratory experiments, HCAs and PAHs have been found to be mutagenic—that is, they. Sorry, our data provider has not provided any external links therefor we are unable to provide a : R. Schoental. Clayson () suggested that, to be carcinogenic, an aromatic amine had to: o poseese two or three con fidgeted aromatic ring systems {~.g., biptleny} or napbthalene) and o have the amino group substituted in the aromatic ring in the pare position to a conjugated aromatic system.

his suggestion has been refined more recently by the clear. Aromatic amines are widely used in dyeing industry as a starting material for manufacturing of different types of azo dyes, such as methyl orange, sunset yellow, ponceau colors.

As aromatic amines take part in many chemical reactions, they are used in chemical industry, for example for manufacturing of petrol and diesel fuel, varnishes, and.

carcinogenic and chronic toxic hazards of aromatic amines— By Mitchell R. Zavon Topics: Journal Departments: Book ReviewsAuthor: Mitchell R. Zavon. Azo dyes are widely used in the food, pharmaceutical, cosmetic, textile and leather industries. They can be reduced by azoreductases in intestinal bacteria, liver cells and skin surface microflora so that aromatic amines are released.

In this study an analytical system for the determination of carcinogenic aromatic amines at the picogram to femtogram level and a Cited by: Over 5, different chemicals are used in hair dye products, some of which are reported to be carcinogenic (cancer-causing) in animals (2–4).

Because so many people use hair dyes, scientists have tried to determine whether exposure to the chemicals in hair coloring products is associated with an increased risk of cancer in people.

Isolated perfused livers from male Wistar rats were used to study acute and chronic toxic effects of carcinogenic aromatic amines. We investigated the hypothesis that aromatic amines can generate reactive oxygen species as part of their by: Suggested Citation:"Carcinogenic Potency and Risk Estimation."National Research Council.

Aromatic Amines: An Assessment of the Biological and Environmental gton, DC: The National Academies Press. doi: /IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man: Some Aromatic Amines, Hydrazine and Related Substances, N-nitroso Compoundsand Miscellaneous Alkylating Agents.

Vol 4 and a great selection of related books, art .